they are consistently closer to the reference image than the average distance of all individual manual segmentations. The results of this method are even better than manual segmentation, i.e. For pre-dilation images a fully automated active contour model, initialized by thresholding, preceded by filtering with a small-scale median filter is the best alternative for manual delineation. While for the post-dilation images no definite conclusions can be drawn, an automated contour model applied to images smoothed with a large kernel appears to be a good alternative to manual contouring. The evaluation has been carried out on 15 images, of which seven are obtained before balloon dilation and eight after balloon dilation. The results are compared with a reference image, obtained from manual editing, by use of four different quality parameters-two based on squared distances and two based on Mahalanobis distances. The combination of different filtering methods and object definition methods results in a total of 21 methods and 80 experiments. After a preprocessing step in which the catheter area is filled with lumen-like grey values, all approaches consist of two steps: (i) smoothing the images with different filtering methods and (ii) extracting the lumen by an object definition method. Light the light of the sun or sky the privilege of. In this study, 21 different (semi-)automated binary-segmentation methods for determining the lumen are compared with manual segmentation to find an alternative for the laborious and subjective procedure of manual editing. Find the legal definition of LUMEN from Blacks Law Dictionary, 2nd Edition. Until now, no accurate, robust and reproducible method to obtain the lumen boundaries from intravascular ultrasound images has been described. The main quantities to be extracted from the data are the size and the shape of the lumen.
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